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About Sikeston, MO

The first explorers and settlers came to a region of cypress swamps and forested prairies. At the beginning of the 20th century, the Little River Drainage District was formed to reclaim the land. This was the world's largest drainage project, moving more earth than completed during the construction of the Panama Canal. In 1541, Spanish explorer Hernando de Soto may have stood upon the Sikeston Ridge, although some historical references dispute this, believing that he traveled further south than Sikeston. The area was claimed by the French as part of La Louisiane, and they ceded it in 1763 to the Spanish after being defeated by Britain in the Seven Years' War.